Cimatron version 12 can remind you to save your file at predefined time intervals. You can turn this option on in the General Preferences area. The save reminder is a small icon that will appear in the lower right corner of your screen. Hovering the mouse on the icon will tell you how much time has elapsed since the last save, and clicking the icon provides a quick way to save the file.
This same Preferences page is where Auto Save can be turned on or off. However, it is important to remember that Auto Save is not a substitute for a true save of the files stored in your job folder, since it only creates restore points to retrieve your data in case of an unexpected system failure.